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Next Generation Osteoarthritis Treatment

CINGAL® is a unique single-injection treatment proven to safely and effectively treat the pain and certain symptoms associated with osteoarthritis (OA)1.

CINGAL® combines two well-established treatments in a single-injection, providing the benefits of both an approved corticosteroid and a proprietary high concentration cross-linked hyaluronic acid formulation.

CINGAL® is a simple treatment performed by a health care professional during an in-office visit.

The corticosteroid reduces inflammation in the joint, providing rapid pain relief within days of injection, while the hyaluronic acid component works in parallel to deliver long lasting pain relief proven to last through 6 months1.

HOW IT WORKS

Joints affected by osteoarthritis typically have lower concentrations of hyaluronic acid in the synovial fluid, the thick liquid that helps cushion and lubricate the joint. As a result, the synovial fluid in osteoarthritic joints has lower viscosity and elasticity than healthy synovial fluid, decreasing its ability to lubricate the joint and absorb shocks.

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Viscosupplements are hyaluronic acid (HA)-based products designed to supplement the body's natural HA, providing significant long-term pain relief from the symptoms of osteoarthritis.

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1. CINGAL 13-01, a randomized, double-blind, placebo-controlled, active comparator Phase III study. Anika Therapeutics, Inc.: study sponsor, Dr. LazloHangody: global principal investigator, SynteractHCR: CRO

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